Human chorionic somatomammotropin is similar to which hormone?

Human chorionic somatomammotropin (hCS), also known as human placental lactogen (hPL), is primarily produced by the placenta during pregnancy. Its structure and function demonstrate notable similarities to growth hormone. Like growth hormone, hCS plays a vital role in regulating maternal metabolism and promoting fetal growth.

hCS acts as an insulin antagonist, increasing the levels of circulating glucose and free fatty acids to ensure that the fetus receives ample nutrition. This function mirrors the growth-promoting effects of growth hormone, which also impacts metabolic processes and supports overall growth and development.

These similarities in hormone function underscore the importance of hCS in pregnancy, particularly in how it facilitates the growth of the developing fetus and adjusts maternal metabolism to meet increased energetic demands. Understanding these connections helps elucidate the critical roles that placental hormones play in maternal-fetal health.