In pregnancy, what is the minimal cortisol level that is diagnostic of Addison's disease?

In the context of diagnosing Addison's disease during pregnancy, low cortisol levels play a crucial role. The minimal cortisol level that is generally considered diagnostic of Addison's disease is typically established around the threshold of less than 3 µg/dL. In pregnant patients, physiological changes can impact cortisol levels, but a cortisol measurement below this specific value is indicative of adrenal insufficiency, which is critical for identifying Addison's disease.

Cortisol levels are essential for various physiological processes during pregnancy, and understanding the normal range helps in distinguishing between physiological adaptations and pathological conditions. In this case, a measurement below 3 µg/dL stands out as a key indicator, reinforcing the need for careful assessment when considering adrenal function in pregnant patients. This diagnostic level ensures that clinicians can initiate timely intervention for any identified adrenal disorders.