What complication is indicated by increased fetal RBC in the vessels?

Study for the Maternal-Fetal Medicine (MFM) Qualifying Exam. Explore comprehensive flashcards and detailed multiple-choice questions, each with hints and explanations to prepare effectively. Achieve success with confidence!

Increased fetal red blood cells (RBCs) in the vessels is primarily indicative of erythroblastosis fetalis, a condition resulting from hemolytic disease in the fetus. This occurs when there is an incompatibility between the mother’s blood type and the fetus’s blood type, commonly seen in Rh or ABO incompatibilities.

When the mother has a different Rh factor than the fetus, her immune system may produce antibodies against the fetal RBCs. These antibodies cross the placenta and lead to the destruction of the RBCs in the fetal circulation, causing the fetus to produce more RBCs in an effort to compensate for the hemolysis. The increase in fetal RBCs is a direct response to this hemolytic process and reflects the body’s attempt to maintain oxygen transport despite the ongoing destruction of red blood cells.

In contrast, while conditions like hydrops fetalis and fetal demise can be associated with elevated fetal RBCs, they often result from other pathological processes that can include severe anemia but are not the direct consequence of the RBC count increase itself. PROM (premature rupture of membranes) does not typically relate to changes in fetal hemoglobin levels or red blood cell production, as it primarily focuses on the integrity of the membranes surrounding the am

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