What does oxidative stress theory suggest as a factor in preeclampsia?

The oxidative stress theory suggests that preeclampsia is associated with injury to endothelial cells caused by free radicals. In the context of preeclampsia, this condition is characterized by the presence of high levels of oxidative stress, which occurs when there is an imbalance between the production of reactive oxygen species (free radicals) and the body’s ability to detoxify these harmful compounds or repair the resulting damage.

During pregnancy, the placenta produces a variety of substances that can increase oxidative stress. The endothelial cells, which line the blood vessels, are particularly vulnerable to damage from these free radicals. When these cells are injured, it can lead to a cascade of events that result in the clinical manifestations of preeclampsia, such as hypertension and proteinuria. Thus, the connection between oxidative stress and endothelial dysfunction is a key component of understanding the pathophysiology of preeclampsia.

The other options do not accurately reflect the role of oxidative stress in the development of preeclampsia. While reduced blood flow to the placenta can be a consequence of endothelial injury, it does not explain the underlying mechanism involving free radicals. Low blood sugar levels do not have a direct link to oxidative stress in preeclampsia, nor does