What is a major concern related to Listeria infections during pregnancy?

Listeria infections during pregnancy pose significant risks primarily to the fetus and newborn, making neonatal meningitis a major concern. Listeria monocytogenes can cross the placental barrier and affect the developing fetus. When an infection occurs during pregnancy, it can lead to premature delivery, stillbirth, or serious health complications for the infant upon delivery, including meningitis. This is a severe and potentially life-threatening condition where the membranes surrounding the brain and spinal cord become inflamed.

While maternal fever is indeed a symptom of listeriosis and can indicate an infection, it is more of a symptom than a direct consequence impacting the fetus or newborn. Maternal chronic fatigue may occur in some cases of infection but is not specifically associated with Listeria. Fetal malformations, while a concern for various maternal infections or conditions during pregnancy, are not typically associated with Listeria infections. Instead, Listeria is more closely linked to severe outcomes like neonatal meningitis or sepsis, which highlight the importance of prevention and monitoring in pregnant individuals.