What is the function of prostaglandin dehydrogenase in fetal development?

Prostaglandin dehydrogenase plays a crucial role in the regulation of prostaglandin levels during fetal development. Its primary function is to catalyze the degradation of prostaglandins, which are lipid compounds that have various functions in inflammation, tissue remodeling, and as mediators in smooth muscle contraction, among other roles. By degrading prostaglandins, prostaglandin dehydrogenase helps maintain an appropriate balance of these signaling molecules, which is particularly important in the fetal environment and during labor.

This balance is essential as excessive prostaglandin levels can lead to premature uterine contractions and other complications during pregnancy. Therefore, the enzymatic action of prostaglandin dehydrogenase is vital in controlling the local levels of prostaglandins to promote adequate fetal development and ensure a successful pregnancy outcome.