What is the therapeutic aim for maternal PaO2 to maintain adequate oxygen saturation during pregnancy?

The therapeutic aim for maternal arterial oxygen tension (PaO2) during pregnancy is to maintain a level greater than 60 mmHg. This target is crucial because adequate oxygen saturation is imperative for both maternal health and fetal well-being. During pregnancy, the physiological changes increase maternal oxygen demand and modify gas exchange processes. Ensuring a PaO2 above 60 mmHg helps to optimize oxygen transport to the fetus, thereby supporting its growth and development.

Maintaining a PaO2 at or below this level can risk fetal hypoxia and associated complications, while levels significantly above 60 mmHg are typically unnecessary and may indicate hyperoxia, which can also have adverse effects. Thus, targeting PaO2 above 60 mmHg strikes a balance between sufficient oxygenation for the mother and fetus and minimizing potential risks associated with excessive oxygen levels.