What laboratory change is associated with increased agiotensin II sensitivity in preeclampsia?

In preeclampsia, there is a significant alteration in the renin-angiotensin system. The condition is characterized by increased sensitivity to angiotensin II, which is largely due to elevated levels of renin. This increase in renin contributes to heightened vasoconstrictive responses, leading to hypertension and contributing to the pathophysiology of preeclampsia.

In preeclampsia, the hyperactivity of the renin-angiotensin system causes an imbalance between vasodilators and vasoconstrictors. Increased renin leads to higher levels of angiotensin II, resulting in elevated blood pressure and decreased placental perfusion. The sensitivity of tissues to angiotensin II is also enhanced due to various factors associated with preeclampsia.

This laboratory change is crucial in understanding the progression of preeclampsia and helps guide management strategies. Other choices might reflect different aspects of preeclampsia or be facets of the condition, but they do not specifically relate to the increased sensitivity to angiotensin II as effectively as the increase in renin does.