When performing PUBS for NAIT, which of the following is true?

When performing Percutaneous Umbilical Blood Sampling (PUBS) for the management of Neonatal Alloimmune Thrombocytopenia (NAIT), conducting the procedure under ultrasound guidance is essential. Ultrasound helps in accurately locating the umbilical cord and ensures that the needle is inserted safely into the fetal vessel while minimizing the risk of injury to the fetus and surrounding structures. This guidance is crucial for both the success of the sampling and the safety of the procedure.

Understanding the context of PUBS in NAIT, it is important to note that while complications can occur, ultrasound guidance significantly decreases these risks. Additionally, PUBS is not considered a first-line treatment; instead, it is typically used when there is severe fetal thrombocytopenia, as a subsequent management option following other treatments. Fetal monitoring is also necessary during and after the procedure to ensure the well-being of the fetus, helping in the immediate assessment of any consequences resulting from the procedure.