When should antenatal testing begin for patients with Sickle Cell Disease?

Antenatal testing for patients with Sickle Cell Disease (SCD) typically begins around 32-34 weeks of gestation. This timing is crucial because patients with SCD are at increased risk for complications such as vaso-occlusive crises, acute chest syndrome, and fetal growth restriction, particularly as pregnancy progresses. Initiating surveillance during this period allows for close monitoring of both maternal and fetal well-being.

Beginning at 32-34 weeks allows healthcare providers to assess for any adverse events or complications that may arise as the pregnancy nears term. The aim is to ensure timely interventions if necessary, such as planning for delivery in a controlled setting that can address potential complications for the mother and baby.

The earlier options of 24-26 weeks and 30-32 weeks may not adequately balance the need for intensive monitoring with the risks associated with earlier interventions, while the later options of 36-38 weeks would miss the critical window for early detection and management of potential complications. Thus, the timing of 32-34 weeks becomes a standard recommendation for initiating antenatal testing in patients with Sickle Cell Disease.