Which organism is most commonly associated with Lyme disease?

Lyme disease is primarily associated with Borrelia burgdorferi, a spirochetal bacterium. This organism is transmitted to humans through the bite of infected black-legged ticks, commonly known as deer ticks. Infection with Borrelia burgdorferi can lead to a range of symptoms, including erythema migrans (the characteristic "bull's-eye" rash), fever, fatigue, and joint pain.

Understanding the association of the organism with Lyme disease is essential for recognizing the clinical presentation and for guiding appropriate diagnosis and treatment. It is also important to note that the other organisms listed do not cause Lyme disease and are associated with different infections or conditions. This knowledge assists in differentiating between various tick-borne diseases and understanding their epidemiology.