Which treatment is recommended for HPV during pregnancy?

Trichloroacetic acid (TCA) is recommended for the treatment of HPV (human papillomavirus) lesions during pregnancy because it is a safe, effective option for managing genital warts that can occur due to HPV infection. TCA works by chemically destroying the wart tissue without significant risk to the fetus. Its localized application minimizes systemic absorption and potential adverse effects.

In contrast, other treatments such as imiquimod, while effective, are generally not recommended during pregnancy due to limited safety data, and concerns over the systemic effects that could potentially impact the developing fetus. Similarly, agents like 5-Fluorouracil (5-FU) and interferon are not typically used during pregnancy due to their potential teratogenic effects and other risks that could harm fetal development. Therefore, TCA is the preferred option when treatment for HPV-related lesions is needed during pregnancy.