Which type of hepatitis carries the highest risk of becoming chronic?

Hepatitis C has a significant association with the development of chronic infection, which is a key factor in determining its public health impact. Unlike Hepatitis A, which is primarily an acute infection and does not become chronic, Hepatitis C can persist in the liver for years or even decades. The likelihood of developing chronic Hepatitis C is much higher compared to Hepatitis B and Hepatitis D.

While Hepatitis B can also lead to chronic infection, the rates are lower compared to Hepatitis C, especially in adults. Additionally, Hepatitis D cannot occur without Hepatitis B; thus, its chronicity is inherently linked to the presence of a Hepatitis B infection. The chronic nature of Hepatitis C leads to long-term health complications, including cirrhosis and hepatocellular carcinoma, further emphasizing its risk profile. Hence, among all the forms of viral hepatitis, Hepatitis C stands out as the one that carries the highest risk of chronicity.